The nightlife can start on the beach in early afternoon and has be known to end up back at the beach after a dizzying 24 hours. Slaughters is located at Lazaro Cardenas 254 and is open every day from 6pm until 6am. Gay-Friendly Bars & Nightlife in Puerto Vallarta. The bar in the front plays a mix of pop/music and is the perfect place to grab a few drinks with your mates before heading to one of the clubs. The back is the nightclub part (see below). The venue has two sections, the front smaller section, which is where the bar is. Slaughters Portland: CC Slaughters is a gay bar and nightclub originally from Portland, Oregon in the United States that also has a location in Puerto Vallarta.Blondies is located at 115 Pulpito and is open daily from 11am until 2am. The pop art decor with matching staff attire is so cool and they host regular events, particularly bear parties. Blondies: Blondies Loft and Slushbar is another very unique (but awesome) concept – a bar that serves alcoholic slushies! These aren't your regular slushies though, they are premium frozen cocktails like the “Big Tease Blondie” – a mix of Absolut vanilla vodka, dark chocolate liqueur and Bailey's Irish Cream – yummm! There are also more traditional cocktails (and snacks) available in the second-floor loft.Paco's Ranch can be found at Ignacio Luis Vallarta 278 and is open Wednesday to Sundays from 10pm until 5am. The drag shows are a hit, make sure you get a spot on the second-floor balcony for the best views. Enjoy some fun in the sun at Mantamar Beach Club Bar & Sushi, sitting on the most famous gay beach in Puerto Vallarta: Los Muertos. Paco's Ranch: Paco's is another cowboy-themed gay bar but it's also a club where you can dance the night away (see more about this below).